The Effects of Intracoeliac Injections of Alpha-adrenergic Agonists and Veratridine on Reticuloruminal Motility and the Evocation of Rumination in Sheep
| Autor: | D. P. Campion, B. F. Leek |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Xylazine
Agonist medicine.medical_specialty Rumen Adrenergic receptor medicine.drug_class Motility Adrenergic Clonidine Pathology and Forensic Medicine Phenylephrine chemistry.chemical_compound Internal medicine medicine Animals Veratridine Sheep General Veterinary Imidazoles Medetomidine Endocrinology Injections Intra-Arterial chemistry Rumination Reticular connective tissue medicine.symptom Gastrointestinal Motility Adrenergic alpha-Agonists medicine.drug |
| Zdroj: | Journal of Veterinary Medicine Series A. 42:443-451 |
| ISSN: | 1439-0442 0931-184X |
| Popis: | Summary The ability of alpha-2 adrenoreceptor agonists and veratridine to evoke rumination and to modify reticular motility in adult Suffolk-cross sheep when injected by close-arterial injection into the forestomach was investigated. The specific alpha-2 adrenoreceptor agonists, xylazine and medetomidine, evoked rumination and increased reticular motility. The Na+ channel activator veratridine also evoked rumination and dramatically increased reticular motility. In contrast, injection of the alpha-1 adrenoreceptor agonist, phenylephrine, was ineffectual in evoking rumination and resulted in reduced reticular motility. It is concluded that the evocation of rumination by alpha-2 adrenergic agonists and veratridine is probably due to the activation of sensory nervous receptors (epithelial receptors) located in the reticulorumen. |
| Databáze: | OpenAIRE |
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