Diagnostic Utility of the Simplified Perfusion Fraction for Identifying Myocardial Injury in Patients With Reperfused ST ‐segment Elevation Myocardial Infarction

Autor: Jianrong Xu, Jun Pu, Jiani Hu, Lara M. Fahmy, Lian-Ming Wu, Jie He, Tong-Tong Han, Shiteng Suo, Dong-Aolei An, Bing-Hua Chen
Rok vydání: 2020
Předmět:
Zdroj: Journal of Magnetic Resonance Imaging. 53:516-526
ISSN: 1522-2586
1053-1807
DOI: 10.1002/jmri.27310
Popis: BACKGROUND Acute myocardial infarction (AMI) is a disease with high morbidity and mortality worldwide and the evaluation of myocardial injury and perfusion status following myocardial ischemia and reperfusion is of clinical value. PURPOSE To assess the diagnostic utility of simplified perfusion fraction (SPF) in differentiating salvage and infarcted myocardium and its predictive value for left ventricular remodeling in patients with reperfusion ST-segment elevation myocardial infarction (STEMI). STUDY TYPE Prospective. POPULATION Forty-one reperfused STEMI patients and 20 healthy volunteers. FIELD STRENGTH/SEQUENCE 3.0T MRI. The MR examination included cine, T2 -short tau inversion recovery (T2 -STIR), first pass perfusiong (FPP)，phase sensitive inversion recovery (PSIR), and diffusion-weighted imaging (DWI). ASSESSMENT SPF values among different myocardium regions (infarcted, salvaged, remote, and MVO) and stages of reperfused STEMI patients as well as normal controls were measured. The diagnostic utility of SPF values in differentiating salvaged and infarcted myocardium was assessed. STATISTICAL ANALYSIS Independent t-test and the Mann-Whitney U-test. Logistic regression. RESULTS SPF values in healthy controls were not significantly different than SPF values in the remote myocardium of patients (40.09 ± 1.47% vs. 40.28 ± 1.93%, P = 0.698). In reperfusion STEMI patients, SPF values were lower in infarcted myocardium compared to remote and salvaged myocardium (32.15 ± 2.36% vs. 40.28 ± 1.93%, P
Databáze: OpenAIRE
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