Overview of C3 Glomerulopathy
| Autor: | Vimal Master Sankar Raj, Deepa H. Chand, Roberto Gordillo |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
business.industry kidney disease 030232 urology & nephrology C3 deposition atypical HUS Histological feature Glomerulonephritis Review complement C3 medicine.disease Pediatrics Complement system 03 medical and health sciences 030104 developmental biology 0302 clinical medicine children Glomerulopathy Pediatrics Perinatology and Child Health Immunology Glomerulus Medicine C3 glomerulopathies business Neuroscience |
| Zdroj: | Frontiers in Pediatrics |
| ISSN: | 2296-2360 |
| Popis: | C3 glomerulopathy is an umbrella term, which includes several rare forms of glomerulonephritis (GN) with underlying defects in the alternate complement cascade. A common histological feature noted in all these GN is dominant C3 deposition in the glomerulus. In this review, we will provide an overview of the complement system as well as mediators, with an introduction to pharmaceutical agents that can alter the pathway. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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