The localization of [3H]-desipramine in central nerve terminals studied with electron microscope autoradiography and subcellular fractionation
| Autor: | David Samuel, Anat Biegon, Ziva Yavin, R. Hofstein |
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| Rok vydání: | 1979 |
| Předmět: |
Male
Receptors Drug Analytical chemistry Tritium law.invention Cellular and Molecular Neuroscience law Desipramine medicine Animals Molecular Biology Myelin Sheath Pharmacology Chemistry Brain Cell Biology Rat brain Rats Subcellular distribution Microscopy Electron Membrane Synapses Biophysics Molecular Medicine Cell fractionation Electron microscope Caudate Nucleus medicine.drug Subcellular Fractions Synaptosomes |
| Zdroj: | Experientia. 35(9) |
| ISSN: | 0014-4754 |
| Popis: | The cellular and subcellular distribution of [3H]-desipramine (DMI) in rat brain was studied by electron microscope (EM) autoradiography and by subcellular fractionation. A considerable proportion of label was found to be bound to the membranes of presynaptic nerve terminals, as well as to sites inside those terminals. |
| Databáze: | OpenAIRE |
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