Different serotypes of dengue virus (DENV) imported by Polish travellers from dengue endemic areas to Poland
| Autor: | Agnieszka Wroczyńska, Maria Racewicz, Joanna Stańczak, Beata Szostakowska, Wacław Nahorski, Anna Kuna, Beata Biernat |
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| Rok vydání: | 2015 |
| Předmět: |
Serotype
viruses Aedes aegypti Dengue virus Serogroup medicine.disease_cause Dengue fever Microbiology Dengue medicine Humans Infective virus Retrospective Studies Travel biology Basic Local Alignment Search Tool virus diseases Endemic area General Medicine Dengue Virus biochemical phenomena metabolism and nutrition biology.organism_classification medicine.disease Virology GenBank Poland Sequence Alignment |
| Zdroj: | International Maritime Health. 66:72-76 |
| ISSN: | 2081-3252 1641-9251 |
| DOI: | 10.5603/imh.2015.0018 |
| Popis: | Background: Dengue viruses are the most widespread arboviruses (transmitted mainly by Aedes aegypti and Ae. albopictus mosquitoes), which have shown an unexpected geographic expansion. There are four dengue virus serotypes: DENV-1, DENV-2, DENV-3, and DENV-4. Subsequent infections increase the risk of developing severe dengue fever. Materials and methods: Samples from travellers returning from the endemic area of dengue fever were examined with the reverse transcription-polymerase chain reaction method. Primers amplified 743 bp fragment of the NS5 and 3’UTR genomic region of mosquito-borne flaviviruses of JEV group were used. Results: The sequences from the 10 examined patients were compared to available DENV sequences in GenBank database and the basic local alignment search tool (BLAST) results confirmed that the infective virus was DENV-1 (6 patients), DENV-2 (2 patients) and DENV-3 (2 patients). Conclusions: For the first time in Poland, dengue virus serotypes were determined in travellers returning from dengue-endemic areas. |
| Databáze: | OpenAIRE |
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