Classifying dermoscopic patterns of naevi in a case-control study of melanoma

Autor: Helmut Schaider, Seamus R. McWhirter, Katie J. Lee, Marco Ardigò, Glen Wimberley, Natalie Ling, David L. Duffy, Philip McClenahan, Richard A. Sturm, H. Peter Soyer
Jazyk: angličtina
Rok vydání: 2017
Předmět:
0301 basic medicine
Melanomas
Pigments
Male
Research Validity
Skin Neoplasms
Medical Doctors
Health Care Providers
lcsh:Medicine
Pathology and Laboratory Medicine
Spearman's rank correlation coefficient
Biochemistry
Correlation
030207 dermatology & venereal diseases
0302 clinical medicine
Medicine and Health Sciences
Medical Personnel
lcsh:Science
Melanoma
Mathematics
Observer Variation
Nevus
Pigmented
Multidisciplinary
Research Assessment
Middle Aged
Professions
Oncology
Feature (computer vision)
Research Design
Physical Sciences
Keratins
Female
Observer variation
Research Article
Adult
medicine.medical_specialty
Materials Science
Dermoscopy
Dermatology
Research and Analysis Methods
03 medical and health sciences
Signs and Symptoms
Diagnostic Medicine
General Practitioners
Physicians
Terminology as Topic
medicine
Humans
Melanoma diagnosis
Materials by Attribute
Analysis of Variance
lcsh:R
Case-control study
Cancers and Neoplasms
Biology and Life Sciences
Proteins
Reproducibility of Results
Health Care
Cytoskeletal Proteins
030104 developmental biology
Case-Control Studies
People and Places
Lesions
lcsh:Q
Population Groupings
Zdroj: PLoS ONE
PLoS ONE, Vol 12, Iss 10, p e0186647 (2017)
ISSN: 1932-6203
Popis: Changes in dermoscopic patterns of naevi may be associated with melanoma; however, there is no consensus on which dermoscopic classification system is optimal. To determine whether different classification systems give comparable results and can be combined for analysis, we applied two systems to a case-control study of melanoma with 1037 participants: 573 classified using a "1/3 major feature" system, 464 classified based on rules of appearance, and 263 classified with both criteria. There was strong correlation for non-specific (Spearman R = 0.96) and reticular (Spearman R = 0.82) naevi, with a slight bias for globular naevi with the rules of appearance system. Inter-observer reliability was high for the rules of appearance system, particularly for reticular naevi (Pearson >0.97). We show that different classification systems for naevi can be combined for data analysis, and describe a method for determining what adjustments may need to be applied to combine data sets.
Databáze: OpenAIRE
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