Blood stream infections (BSI) in severe burn patients—Early and late BSI: A 9-year study
| Autor: | Ayelet Raz-Pasteur, Yehuda Ullmann, Khetam Hussein, Renato Finkelstein, Dana Egozi |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Adult
Male Pediatrics medicine.medical_specialty Time Factors Adolescent Bacteremia Critical Care and Intensive Care Medicine medicine.disease_cause Sepsis Young Adult medicine Humans Severe burn Young adult Aged Retrospective Studies Aged 80 and over Bacteria Pseudomonas aeruginosa business.industry Incidence Incidence (epidemiology) Fungi Retrospective cohort study General Medicine Middle Aged bacterial infections and mycoses medicine.disease Emergency Medicine Female Surgery Burns business Fungemia human activities Blood stream |
| Zdroj: | Burns. 39:636-642 |
| ISSN: | 0305-4179 |
| Popis: | Bloodstream infections (BSI) and sepsis are among the most common complications occurring in severe burn patients. This study was designed to evaluate changes in BSI pathogens over almost a decade in severe burn patients at Rambam Healthcare Campus, and BSI occurrence during early and late hospitalization periods. Retrospective computerized data was retrieved from all severe burn patients hospitalized in our institution during the years 2001-2009. BSI in the first week was defined as early BSI, and in the second week and beyond, late BSI. Of 159 severe burns patients, 74 had at least one BSI episode. Most first BSI episodes were diagnosed during the first week of hospitalization. In late BSI, an increased prevalence of resistant bacteria (methicillin-resistant Staphylococcus aureus [MRSA], carbapenem-resistant Klebsiella pneumoniae [CRKP], imipenem-resistant Pseudomonas aeruginosa [PSE-IMP]) and Candida spp. were observed. However, over the 9-year study period, only CRKP increased significantly. In summary, except for the sudden appearance and increase in CRKP (8% increase; p=0.045), we did not observe a significant change in the BSI pathogen profile over the 9-year period. Nevertheless, over the hospitalization period, there is a clear change in the BSI bacteria profile, especially after 4 weeks of hospitalization. |
| Databáze: | OpenAIRE |
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