Comparison of risk factors and outcome in patients with Enterococcus faecalis vs Enterococcus faecium bacteraemia
| Autor: | J Suppola, Arja Kuikka, Ville Valtonen, Martti Vaara |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Male
Cephalosporin Enterococcus faecium Bacteremia 0302 clinical medicine Risk Factors hemic and lymphatic diseases Enterococcus faecalis 030212 general & internal medicine Finland 0303 health sciences biology Incidence pathological conditions signs and symptoms General Medicine Middle Aged Shock Septic 3. Good health Anti-Bacterial Agents Survival Rate Infectious Diseases Treatment Outcome Drug Therapy Combination Female medicine.drug Microbiology (medical) Adult congenital hereditary and neonatal diseases and abnormalities medicine.medical_specialty medicine.drug_class Microbial Sensitivity Tests Neutropenia Statistics Nonparametric Microbiology 03 medical and health sciences Internal medicine medicine Humans Risk factor Survival rate Gram-Positive Bacterial Infections Aged Retrospective Studies General Immunology and Microbiology 030306 microbiology business.industry Clindamycin biochemical phenomena metabolism and nutrition bacterial infections and mycoses medicine.disease biology.organism_classification business |
| Zdroj: | Scandinavian journal of infectious diseases. 30(2) |
| ISSN: | 0036-5548 |
| Popis: | The purpose of our study was to determine retrospectively the risk factors for the acquisition of Enterococcus faecalis vs E. faecium bacteraemia, as well as the clinical outcomes of these patients. 62 patients with Enterococcus faecalis bacteraemia were compared to 31 patients with E. faecium bacteraemia. Haematologic malignancies, neutropenia, high-risk source and previous use of aminoglycosides, carbapenems, cephalosporins and clindamycin were significantly associated with E. faecium bacteraemia. Instead, urinary catheterization was found to be related to Enterococcus faecalis bacteraemia. The mortality rates within 7 d and 30 d were 13% and 27%, respectively, in patients with E. faecalis bacteraemia and 6% and 29%, respectively, in patients with E. faecium bacteraemia. There was no difference in mortality between E. faecalis and E. faecium bacteraemia, nor was there a difference in seriousness of disease at the time of bacteraemia. In the subgroups of patients with monomicrobial or clinically significant E. faecalis vs E. faecium bacteraemia, the mortality rates were similar to the results of all subjects. Our results do not support the theory that E. faecium would be a more virulent organism than E. faecalis. |
| Databáze: | OpenAIRE |
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