An analytical evaluation of eight on-site oral fluid drug screening devices using laboratory confirmation results from oral fluid
| Autor: | Rene Mathijssen, Sara-Ann Legrand, Kari Vimpari, Anna Pehrsson, Pirjo Lillsunde, Alain Verstraete, Sjoerd Houwing, Kristof Pil, Tom Blencowe, Trudy Van der Linden, Beitske E. Smink |
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| Rok vydání: | 2010 |
| Předmět: |
Drug
Narcotics medicine.medical_specialty Automobile Driving media_common.quotation_subject Poison control Sensitivity and Specificity Pathology and Forensic Medicine Forensic Toxicology medicine Drug test Humans Amphetamine Saliva Driving under the influence media_common medicine.diagnostic_test business.industry celebrities Forensic toxicology Reproducibility of Results MDMA Surgery celebrities.reason_for_arrest Europe Substance Abuse Detection Drugwipe test Emergency medicine business Law medicine.drug |
| Zdroj: | Forensic science international. 208(1-3) |
| ISSN: | 1872-6283 |
| Popis: | The performance of eight on-site oral fluid drug screening devices was studied in Belgium, Finland and the Netherlands as a part of the EU-project DRUID. The main objective of the study was to evaluate the reliability of the devices for testing drivers suspected of driving under the influence of drugs (DUID). The performance of the devices was assessed by their ability to detect substances using cut-offs which were set at sufficiently low levels to allow optimal detection of positive DUID cases. The devices were evaluated for the detection of amphetamine(s), cannabis, cocaine, opiates and benzodiazepines when the relevant test was incorporated. Methamphetamine, MDMA and PCP tests that were included in some devices were not evaluated since there were too few positive samples. The device results were compared with confirmation analysis results in oral fluid. The opiates tests appeared to perform relatively well with sensitivity results between 69 and 90%. Amphetamines and benzodiazepines tests had lower sensitivity, although the DrugWipe test evaluated was promising for amphetamine. In particular, it is evident that the cannabis and cocaine tests of the devices still lack sensitivity, although further testing of the cocaine tests is desirable due to the low prevalence and low concentrations encountered in this study. |
| Databáze: | OpenAIRE |
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