Cigarette Smoking and Human Pulmonary Macrophages
Autor: | Glenn A. Warr, R. Russell Martin |
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Rok vydání: | 1977 |
Předmět: |
Bronchial Lavage
Complement receptor 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Cigarette smoking Immunity Humans Medicine 030212 general & internal medicine Lung Macrophage Migration-Inhibitory Factors chemistry.chemical_classification Immunity Cellular biology business.industry Macrophages Smoking General Medicine biology.organism_classification Migration Inhibitory Factor Enzyme chemistry Pulmonary Macrophages Immunology Carcinogens Binding Sites Antibody business Bacteria |
Zdroj: | Hospital Practice. 12:97-104 |
ISSN: | 2377-1003 2154-8331 |
Popis: | Bronchial lavage recovers about four times as many free cells, particularly pulmonary alveolar macrophages, from smokers as from nonsmokers. These cells display altered surface morphology, increased lysosomal enzymes, fewer complement receptors, decreased phagocytic activity against some bacteria, and unresponsiveness to migration inhibitory factor, possibly indicating a defect in cell-mediated immunity. |
Databáze: | OpenAIRE |
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