Radiotherapy alters the composition, structural and mechanical properties of root dentin in vitro
| Autor: | Marilia Mattar de Amoêdo Campos Velo, Aymée Shiota, Ana Tarsila Fonseca Souza, Linda Wang, Ana Laura Herrera Farha, Paulo Sérgio da Silva Santos, Simone Zuquerato Sansavino, Heitor Marques Honório |
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| Rok vydání: | 2018 |
| Předmět: |
Molar
Scanning electron microscope Dentistry In Vitro Techniques 03 medical and health sciences 0302 clinical medicine X-Ray Diffraction stomatognathic system Hardness Dentin medicine Humans Irradiation Dehydration Tooth Root General Dentistry Root caries business.industry Chemistry Spectrometry X-Ray Emission 030206 dentistry medicine.disease stomatognathic diseases medicine.anatomical_structure CÁRIE RADICULAR 030220 oncology & carcinogenesis Microscopy Electron Scanning Molar Third Composition (visual arts) business |
| Zdroj: | Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP |
| Popis: | Post-radiation dental lesions affect mainly the cervical area of the tooth. Until now, there are quite few evidences regarding the effects of radiation exposure on root dentin breakdown. To better understand this effect, we used human root dentin specimens obtained from third molars from similarly aged individuals. Twenty specimens were analyzed by the surface hardness (SH), energy-dispersive X-ray spectroscopy (EDX), and X-ray diffraction (XRD) to evaluate the baseline properties of their root dentin. Other six human teeth were prepared and analyzed by scanning electron microscopy (SEM). Then the specimens were randomly distributed between two groups (n = 13 per group) and irradiated with a total dose of 55 or 70 Gy in a linear accelerator. The percentage of EDX and surface hardness loss (%SHL) were determined based on measurements before and after irradiation. The specimens were also analyzed after irradiation by SEM and XRD. The Ca/P weight ratio was calculated. Based on SEM analysis, radiation exposure induced dehydration of the dentin. The Ca/P weight ratio decreased (p = 0.0045). The %SHL of specimens irradiated with 70 Gy was higher than that of the 55-Gy group (p |
| Databáze: | OpenAIRE |
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