Improvement in injury induced hypocalcia by high-dose naloxone intervention
| Autor: | Gary Edward Hollinden, Phillip Fox, Bradford T. Stokes |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
medicine.medical_specialty
Central nervous system chemistry.chemical_element (+)-Naloxone Calcium Naloxone Hydrochloride Lesion Dogs Internal medicine Medicine Animals Molecular Biology Spinal Cord Injuries biology business.industry Naloxone General Neuroscience Fissipedia biology.organism_classification Spinal cord Endocrinology medicine.anatomical_structure Traumatic injury chemistry Anesthesia Neurology (clinical) medicine.symptom business Extracellular Space Developmental Biology |
| Zdroj: | Brain research. 290(1) |
| ISSN: | 0006-8993 |
| Popis: | Naloxone hydrochloride was used to re-establish normal calcium activities in the extracellular space of the injured spinal cord. The micromolar levels of calcium which occur immediately after injury were improved above control values by 1 h 30 min post-injury; normal activities occured at 2 h 45 min. Such a restitution of ionic levels after injury may contribute to the beneficial effects of naloxone in traumatic injury. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|