Functional consequences of blood clotting in insects
| Autor: | Michael T. Siva-Jothy, Eleanor R. Haine, Jens Rolff |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Lipopolysaccharides
Amaranth Dye Hemocytes animal structures media_common.quotation_subject Immunology Insect Immune system In vivo Hemolymph Animals Periplaneta Blood Coagulation media_common Enzyme Precursors biology Monophenol Monooxygenase Effector biology.organism_classification In vitro Ringer's Solution Cell biology Muramidase Isotonic Solutions American cockroach Catechol Oxidase Developmental Biology |
| Zdroj: | Developmental & Comparative Immunology. 31:456-464 |
| ISSN: | 0145-305X |
| DOI: | 10.1016/j.dci.2006.08.004 |
| Popis: | Recent in vitro studies have revealed several important aspects of the biochemical and cellular processes involved in insect blood clotting. However, in vivo empirical studies of the functional consequences of clotting are lacking, despite the role of coagulation in wound-healing, preventing infection, and its homology with vertebrate wound repair. Here we present results of the in vivo effects of haemolymph coagulation and its consequences on the spatial disposition of immune activity, in the American cockroach Periplaneta americana. Our results demonstrate that clotting: (1) localises immune effectors in the vicinity of a breach of the cuticle; (2) restricts the spread of invasive particles across the haemocoel, and (3) is greater when wounding is associated with non-self. Our results demonstrate that haemolymph coagulation has major functional consequences, the most important of which is the compartmentalisation of the open haemocoel. |
| Databáze: | OpenAIRE |
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