Association of Alcohol Consumption After Development of Heart Failure With Survival Among Older Adults in the Cardiovascular Health Study
| Autor: | Kenneth J. Mukamal, Bruce M. Psaty, Phyllis K. Stein, Jorge R. Kizer, David L. Brown, Eric Novak, Justin S. Sadhu |
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| Rok vydání: | 2018 |
| Předmět: |
business.industry
Research media_common.quotation_subject Cardiovascular health Cardiology General Medicine 030204 cardiovascular system & hematology Abstinence medicine.disease New diagnosis 3. Good health Online Only 03 medical and health sciences 0302 clinical medicine Survival benefit Heart failure Medicine 030212 general & internal medicine Study analysis Prospective cohort study business Alcohol consumption Original Investigation Demography media_common |
| Zdroj: | JAMA Network Open |
| ISSN: | 2574-3805 |
| Popis: | This cohort study investigates whether the consumption of alcohol after the diagnosis of heart failure among older adults who participated in the Cardiovascular Health Study was associated with increased survival compared with abstinence. Key Points Question What is the association of alcohol consumption after the diagnosis of heart failure with survival among older adults? Findings In this cohort study of 393 older adults with incident heart failure, consumption of 7 or fewer alcoholic drinks per week was significantly associated with increased survival compared with abstinence from alcohol, after controlling for other factors. Meaning Limited alcohol consumption among older adults with incident heart failure may be associated with increased survival. Importance More than 1 million older adults develop heart failure annually. The association of alcohol consumption with survival among these individuals after diagnosis is unknown. Objective To determine whether alcohol use is associated with increased survival among older adults with incident heart failure. Design, Setting, and Participants This prospective cohort study included 5888 community-dwelling adults aged 65 years or older who were recruited to participate in the Cardiovascular Health Study between June 12, 1989, and June 1993, from 4 US sites. Of the total participants, 393 individuals had a new diagnosis of heart failure within the first 9 years of follow-up through June 2013. The study analysis was performed between January 19, 2016, and September 22, 2016. Exposures Alcohol consumption was divided into 4 categories: abstainers (never drinkers), former drinkers, 7 or fewer alcoholic drinks per week, and more than 7 drinks per week. Primary Outcomes and Measures Participant survival after the diagnosis of incident heart failure. Results Among the 393 adults diagnosed with incident heart failure, 213 (54.2%) were female, 339 (86.3%) were white, and the mean (SD) age was 78.7 (6.0) years. Alcohol consumption after diagnosis was reported in 129 (32.8%) of the participants. Across alcohol consumption categories of long-term abstainers, former drinkers, consumers of 1-7 drinks weekly and consumers of more than 7 drinks weekly, the percentage of men (32.1%, 49.0%, 58.0%, and 82.4%, respectively; P |
| Databáze: | OpenAIRE |
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