Thoracic aortic aneurysm and dissection
| Autor: | Valentin Fuster, Kim A. Eagle, Jonathan L. Halperin, Allan S. Stewart, Judith Z. Goldfinger, Michael L. Marin |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Marfan syndrome
medicine.medical_specialty endovascular procedures Turner Syndrome Dissection (medical) Thoracic aortic aneurysm Marfan Syndrome Aortic aneurysm Aneurysm Internal medicine medicine.artery medicine risk factors Thoracic aorta Animals Humans cardiovascular diseases cardiac surgical procedures transforming growth factor beta Aortic dissection Aortic Aneurysm Thoracic business.industry medicine.disease Prophylactic Surgery Surgery Aortic Dissection cardiovascular system Cardiology Ehlers-Danlos Syndrome Cardiology and Cardiovascular Medicine business aortic aneurysm |
| Zdroj: | Journal of the American College of Cardiology. 64(16) |
| ISSN: | 1558-3597 |
| Popis: | Aortic dissection is the most devastating complication of thoracic aortic disease. In the more than 250 years since thoracic aortic dissection was first described, much has been learned about diseases of the thoracic aorta. In this review, we describe normal thoracic aortic size; risk factors for dissection, including genetic and inflammatory conditions; the underpinnings of genetic diseases associated with aneurysm and dissection, including Marfan syndrome and the role of transforming growth factor beta signaling; data on the role for medical therapies in aneurysmal disease, including beta-blockers, angiotensin receptor blockers, and angiotensin-converting enzyme inhibitors; prophylactic surgery for aneurysm; surgical techniques for the aortic root; and surgical and endovascular management of aneurysm and dissection for different aortic segments. |
| Databáze: | OpenAIRE |
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