Cryptochromes: Blue Light Receptors for Plants and Animals

Autor: Anthony R. Cashmore, Jose A. Jarillo, Dongmei Liu, Yingjie Wu
Rok vydání: 1999
Předmět:
Zdroj: Science. 284:760-765
ISSN: 1095-9203
0036-8075
DOI: 10.1126/science.284.5415.760
Popis: Cryptochromes are blue, ultraviolet-A photoreceptors. They were first characterized forArabidopsisand are also found in ferns and algae; they appear to be ubiquitous in the plant kingdom. They are flavoproteins similar in sequence to photolyases, their presumptive evolutionary ancestors. Cryptochromes mediate a variety of light responses, including entrainment of circadian rhythms inArabidopsis,Drosophila, and mammals. Sequence comparison indicates that the plant and animal cryptochrome families have distinct evolutionary histories, with the plant cryptochromes being of ancient evolutionary origin and the animal cryptochromes having evolved relatively recently. This process of repeated evolution may have coincided with the origin in animals of a modified circadian clock based on the PERIOD, TIMELESS, CLOCK, and CYCLE proteins.
Databáze: OpenAIRE
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