Supplemental Figure S3 from The Renin–Angiotensin System Mediates EGF Receptor–Vitamin D Receptor Cross-Talk in Colitis-Associated Colon Cancer

Autor: Marc Bissonnette, Yan Chun Li, Gregory S. Karczmar, Alice Wyrwicz, Loren Joseph, John Hart, Sharad Khare, Joel Pekow, Vani J. Konda, Weicheng Liu, Sumana Sundaramurthy, Maggi Kreisheh, Devkumar Mustafi, Anas Almoghrabi, Farhana Sadiq, Reba Mustafi, Urszula Dougherty
Rok vydání: 2023
DOI: 10.1158/1078-0432.22456947
Popis: Supplemental Figure S3. EGFR suppresses VDR expression in AOM rat tumors. VDR expression in control colonic mucosa and AOM-induced tumors in rats fed AIN-76A chow alone, or chow supplemented with EGFR inhibitor Gefitinib (A+G). Note the decreased VDR expression in tumors from rats fed AIN-76A alone, compared to rats supplemented with Gefitinib. Shown are representative tumors from two rats in each group.
Databáze: OpenAIRE