The clock drawing test as a cognitive screening tool for assessment of hypertension-mediated brain damage

Autor: Augusto Vicario, Gustavo H. Cerezo, A.E. De Cechio, M. Del Sueldo, P. Conti
Rok vydání: 2021
Předmět:
Zdroj: Hipertensión y Riesgo Vascular. 38:13-20
ISSN: 1889-1837
DOI: 10.1016/j.hipert.2020.08.002
Popis: Introduction Hypertension (HTN) is the most frequent cause of subcortical vascular brain injury (VBI) and its cognitive consequences. The aims were to show the usefulness of the Clock Drawing Test (CDT) to detect cognitive impairment in hypertensive patients and to compare it with the Mini-Mental Test (MMSE). Methods A subset of hypertensive patients of the Heart-Brain Study in Argentina was included. Demographic characteristics, vascular risk factors, blood pressure (BP) and schooling level were recorded. The MMSE and CDT tests were used for neurocognitive assessment and Hospital Anxiety Depression scale (HAD) for mood disorder evaluation. Results 1414 hypertensive patients (age 59.7 ± 13.8 years, female (62.3%). The prevalence of cognitive impairment was 20.7% (using MMSE) and 36.1% (using CDT). Among hypertensive patients with normal MMSE (>24) 29.3% had cognitive impairment (abnormal CDT). The CDT was associated with level of education but not with age or mood status. Conclusions The CDT is a useful screening tool to detect hypertension-mediated brain damage earlier (especially in midlife) and is more sensitive than MMSE.
Databáze: OpenAIRE