Quality of life and related variables in patients with ankylosing spondylitis

Autor: Gülümser Aydin, Şebnem Ataman, Engin Çakar, Aylin Rezvani, Erkan Kozanoglu, Derya Bugdayci, Zuhal Altay, Zafer Günendi, Remzi Çevik, Hikmet Kocyigit, Koncuy Sivrioglu, Hatice Bodur, Murat Birtane, Mehmet Kirnap, Ayşen Akıncı, Pelin Yazgan, Mahmut Yener, Murat Karkucak, Tuncay Duruöz, Raikan Soydemir, Lale Altan, Neşe Ölmez, Simin Hepguler, Rezzan Günaydin, Ajda Bal
Přispěvatelé: Kırıkkale Üniversitesi, Uludağ Üniversitesi/Tıp Fakültesi/Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı., Altan, Lale, Sivrioğlu, Koncuy, Çukurova Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Fizik Tedavi ve Rehabilitasyon Anabilim Dalı, Kozanoğlu, Erkan
Rok vydání: 2010
Předmět:
Zdroj: Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation. 20(4)
ISSN: 1573-2649
Popis: Ataman, Sebnem/0000-0003-3570-3825; Duruoz, Mehmet Tuncay/0000-0003-3584-2788; Karkucak, Murat/0000-0002-4348-8398; WOS: 000289481100010 PubMed: 20978859 To evaluate quality of life (QoL) and related variables in patients with ankylosing spondylitis (AS), a chronic inflammatory disease of the spine. Nine-hundred and sixty-two patients with AS from the Turkish League Against Rheumatism AS Registry, who fulfilled the modified New York criteria, were enrolled. The patients were evaluated using the Assessment of SpondyloArthritis International Society core outcome domains including Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), fatigue (BASDAI-question 1), pain (last week/spine/due to AS), Bath Ankylosing Spondylitis Functional Index (BASFI), Bath Ankylosing Spondylitis Metrology Index (BASMI), Bath Ankylosing Spondylitis Radiology Index (BASRI), Maastricht Ankylosing Spondylitis Enthesitis Score (MASES) and two QoL questionnaires (the disease-specific ASQoL and generic the Short Form-36 [SF-36]). The mean ASQoL score was 7.1 +/- A 5.7. SF-36 subscales of general health, physical role and bodily pain had the poorest scores. ASQoL was strongly correlated with disease duration, BASDAI, fatigue, BASFI, BASMI, BASRI, MASES, pain and SF-36 subscales (P < 0.001). SF-36 subscales were also strongly correlated with BASDAI and BASFI. Advanced educational status and regular exercise habits positively affected QoL, while smoking negatively affected QoL. In patients with AS, the most significant variables associated with QoL were BASDAI, BASFI, fatigue and pain. ASQoL was noted to be a short, rapid and simple patient-reported outcome (PRO) instrument and strongly correlated with SF-36 subscales. Wyeth/Pfizer CompanyWyeth The authors express their gratitude to all members of the TRASD AS Study group for their cooperation and to Wyeth/Pfizer Company for the registery sponsorship.
Databáze: OpenAIRE