10-year outcome study of an early intervention program for psychosis compared with standard care service
| Autor: | Hon-Cheong So, Eric Y.H. Chen, Wing Chung Chang, K. C. Yip, Sherry Kit Wa Chan, Se-Fong Hung, Christy Lai Ming Hui, Edwin Ho Ming Lee, Dicky W.S. Chung, Erin C. Dunn, Steve Tso |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male Psychosis Pediatrics medicine.medical_specialty Time Factors Suicide rates Standard care Early Medical Intervention Outcome Assessment Health Care medicine Humans Longitudinal Studies Applied Psychology Service (business) Intervention program business.industry Odds ratio medicine.disease Functional recovery Psychotherapy Psychiatry and Mental health Psychotic Disorders Schizophrenia Hong Kong Female Historical control business |
| Zdroj: | Psychological medicine. 45(6) |
| ISSN: | 1469-8978 0033-2917 |
| Popis: | Background.Despite evidence on the short-term benefits of early intervention (EI) service for psychosis, long-term outcome studies are limited by inconsistent results. This study examined the 10-year outcomes of patients with first-episode psychosis who received 2-year territory-wide EI service compared to those who received standard care (SC) in Hong Kong using an historical control design.Method.Consecutive patients who received the EI service between 1 July 2001 and 30 June 2002, and with diagnosis of schizophrenia-spectrum disorders, were identified and matched with patients who received SC first presented to the public psychiatric service from 1 July 2000 to 30 June 2001. In total, 148 matched pairs of patients were identified. Cross-sectional information on symptomatology and functioning was obtained through semi-structured interview; longitudinal information on hospitalization, functioning, suicide attempts, mortality and relapse over 10 years was obtained from clinical database. There were 70.3% (N = 104) of SC and 74.3% (N = 110) of EI patients interviewed.Results.Results suggested that EI patients had reduced suicide rate (χ2(1) = 4.35, p = 0.037), fewer number [odds ratio (OR) 1.56, χ2 = 15.64, p χ2 = 4.06, p = 0.04), longer employment periods (OR −0.28, χ2 = 14.64, p χ2 = 11.47, df = 1, p = 0.001) over 10 years. At 10 years, no difference was found in psychotic symptoms, symptomatic remission and functional recovery.Conclusions.The short-term benefits of the EI service on number of hospitalizations and employment was sustained after service termination, but the differences narrowed down. This suggests the need to evaluate the optimal duration of the EI service. |
| Databáze: | OpenAIRE |
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