Structural basis for the inhibition of the SARS-CoV-2 main protease by the anti-HCV drug narlaprevir
| Autor: | Wenjie Tan, Hao Song, Yong Feng, Fei Ye, George F. Gao, Lifeng Fu, Hanyi Liao, Jianxun Qi, Yi Shi, Yu Bai |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Cyclopropanes
Drug Cancer Research 2019-20 coronavirus outbreak Letter Proline Coronavirus disease 2019 (COVID-19) medicine.medical_treatment Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) media_common.quotation_subject Hepacivirus lcsh:Medicine Cysteine Proteinase Inhibitors Leucine Genetics medicine Humans Urea Sulfones lcsh:QH301-705.5 Coronavirus 3C Proteases media_common Protease biology SARS-CoV-2 Anti hiv Chemistry lcsh:R COVID-19 biology.organism_classification Virology COVID-19 Drug Treatment lcsh:Biology (General) Drug screening Narlaprevir Structural biology |
| Zdroj: | Signal Transduction and Targeted Therapy Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-3 (2021) |
| ISSN: | 2059-3635 |
| DOI: | 10.1038/s41392-021-00468-9 |
| Databáze: | OpenAIRE |
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