| Autor: |
Laura Kate Gadanec, Tawar Qaradakhi, Kristen Renee McSweeney, John M. Matsoukas, Vasso Apostolopoulos, Louise M Burrell, Anthony Zulli |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Biochemical pharmacology. 208 |
| ISSN: |
1873-2968 |
| Popis: |
Diminazene aceturate (DIZE), a putative angiotensin-converting enzyme 2 (ACE2) activator, elicits relaxation in various animal models. This study aimed to determine the relaxing mechanisms in internal iliac arteries utilised by DIZE in healthy and atherogenic rabbit models. Studies were conducted on internal iliac artery rings retrieved from male New Zealand White rabbits fed a 4-week healthy control (n = 24) or atherogenic diet (n = 20). To investigate pathways utilised by DIZE to promote arterial relaxation, a DIZE dose response [10 |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect