X-Linked Inhibitor of Apoptosis Antagonism: Strategies in Cancer Treatment
| Autor: | Eric C. LaCasse, Herman H. Cheung, Robert G. Korneluk |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Proteasome Endopeptidase Complex
Cancer Research medicine.medical_specialty Programmed cell death Oligonucleotides Apoptosis X-Linked Inhibitor of Apoptosis Protein Endogeny Biology Inhibitor of apoptosis Neoplasms Internal medicine medicine Humans Inhibitor of apoptosis domain fungi Models Immunological food and beverages Genetic Therapy XIAP Endocrinology Oncology Proteasome Protein Biosynthesis Cancer research Antagonism |
| Zdroj: | Clinical Cancer Research. 12:3238-3242 |
| ISSN: | 1557-3265 1078-0432 |
| Popis: | X-linked inhibitor of apoptosis (XIAP), first identified in 1996 ([1][1]), is a member of the IAP family of endogenous caspase inhibitors that blocks the execution of apoptosis. The inhibitory function of XIAP can be reversed by its antagonists, whereas its abundance can be regulated in a proteasome |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|