Creutzfeldt-Jakob disease in a young adult with idiopathic hypopituitarism. Possible relation to the administration of cadaveric human growth hormone
| Autor: | B O Berg, T K Koch, R F Gravina, S J De Armond |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
Adult
Male medicine.medical_specialty Pediatrics medicine.medical_treatment Hypopituitarism Disease Gyrus Cinguli Creutzfeldt-Jakob Syndrome Diabetes mellitus Internal medicine mental disorders medicine Humans Young adult Testosterone business.industry Insulin Thyroid General Medicine medicine.disease Endocrinology medicine.anatomical_structure Growth Hormone business Drug Contamination Hormone |
| Zdroj: | The New England journal of medicine. 313(12) |
| ISSN: | 0028-4793 |
| Popis: | CREUTZFELDT—JAKOB disease, a transmissible subacute degeneration of the central nervous system, is generally considered a disease of older adults.1 We recently evaluated a 20-year-old man with idiopathic hypopituitarism and insulin-dependent diabetes mellitus in whom Creutzfeldt—Jakob disease developed. Since early childhood he had received cadaveric human growth hormone, as well as insulin, thyroid hormone, and more recently testosterone. Case Report The patient, a 20-year-old man, was referred to the University of California, San Francisco, for evaluation of progressive gait instability. His history was complicated by multiple deficiencies of pituitary hormones from infancy, as well as insulin-dependent diabetes mellitus. Hypopituitarism was suggested . . . |
| Databáze: | OpenAIRE |
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