Rituximab-induced Ileocolitis in a Patient with Gastric MALToma: A Case Report and Literature Review
| Autor: | Yoshikazu Tsuzuki, Hidetomo Nakamoto, Taketo Yamada, Rie Shiomi, Kazuya Miyaguchi, Keigo Ashitani, Hideki Ohgo, Hiroyuki Imaeda, Yoshitaka Miyakawa, Atsushi Sasaki, Rei Kim, Atsushi Osaki |
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| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty T cells Colonoscopy ileocolitis Case Report 030204 cardiovascular system & hematology Inflammatory bowel disease Gastroenterology 03 medical and health sciences 0302 clinical medicine Microscopic colitis rituximab Crohn Disease inflammatory bowel disease Internal medicine Internal Medicine Medicine Humans Aged Enterocolitis B cells medicine.diagnostic_test business.industry General Medicine Lymphoma B-Cell Marginal Zone medicine.disease Ulcerative colitis MALToma Lymphoma 030211 gastroenterology & hepatology Rituximab Bloody diarrhea Colitis Ulcerative medicine.symptom business medicine.drug |
| Zdroj: | Internal Medicine |
| ISSN: | 1349-7235 |
| Popis: | Rituximab (RTX) is effective for treating cancer, but reports of RTX-associated enterocolitis are limited. We herein report the case of a 65-year-old man who developed RTX-induced ileocolitis. He was diagnosed with gastric mucosa-associated lymphoid tissue lymphoma (MALToma) and treated with RTX. He complained of bloody diarrhea after RTX. Mucosal inflammation on colonoscopy indicated RTX-induced ileocolitis. He was treated with corticosteroids, and his symptoms improved. We reviewed the RTX-associated gastrointestinal adverse events and classified the features into ulcerative colitis, Crohn's disease, microscopic colitis, and ileocolitis. To our knowledge, this is the first case of a Japanese patient who developed RTX-induced ileocolitis. |
| Databáze: | OpenAIRE |
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