Observations of rat ovarian-splenic consecutive transplants
| Autor: | S. Lee, I.C. Hong, C.D. Pivetti, S. Nam, Paul L. Wolf, Ruben F. Gittes, S. Bai, S.T. Niewiadomski, K. Kim, Chang H. Yoo |
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| Rok vydání: | 2003 |
| Předmět: |
Reoperation
medicine.medical_specialty Pathology medicine.medical_treatment Ovariectomy Ovary Dysgerminoma Ovarian Follicle Internal medicine medicine Animals Ovarian Neoplasms Life span business.industry Spleen transplantation Organ Transplantation medicine.disease Tumor formation Castrated Female Rats medicine.anatomical_structure Endocrinology Cell Transformation Neoplastic Rats Inbred Lew Models Animal Surgery Female business Spleen |
| Zdroj: | Microsurgery. 23(5) |
| ISSN: | 0738-1085 |
| Popis: | We examined the results after implantation of ovarian follicles by various modes in a total of 82 cases. One or five ovarian follicles were implanted into spleens in castrated female rats. In 20 cases among these, each five follicles were implanted into native and transplanted spleens after spleen transplantation (double implantation of the ovary). Through consecutive spleen transplantation, we observed the results beyond the rat's life span for a limited period. In many cases, we found a more aggressive form of malignant tumor, i.e., dysgerminoma. We present the results and discuss the modes of implantations and possible pathogenetic mechanisms of tumor formation. |
| Databáze: | OpenAIRE |
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