Metabolic rate and substrate utilisation resilience in men undertaking polar expeditionary travel

Autor: Jamie Facer-Childs, Christopher H.E. Imray, John Hattersley, Oliver Stoten, Adrian J. Wilson, C. Doug Thake
Jazyk: angličtina
Rok vydání: 2019
Předmět:
0301 basic medicine
Metabolic Analysis
Male
Bioenergetics
Physiology
Energy balance
Biochemistry
Fats
0302 clinical medicine
Weight loss
Medicine and Health Sciences
Medicine
Multidisciplinary
Organic Compounds
Thermoregulation
Substrate (marine biology)
Lipids
Chemistry
Bioassays and Physiological Analysis
Physiological Parameters
Adipose Tissue
Physical Sciences
Expeditions
Carbohydrate Metabolism
medicine.symptom
Research Article
Adult
Science
Carbohydrates
Antarctic Regions
Carbohydrate metabolism
Body weight
Research and Analysis Methods
03 medical and health sciences
Animal science
Basal Metabolic Rate Measurement
Weight Loss
Humans
Exertion
Nutrition
business.industry
Organic Chemistry
Body Weight
Chemical Compounds
Biology and Life Sciences
Diet
030104 developmental biology
Metabolism
business
Energy Intake
Energy Metabolism
030217 neurology & neurosurgery
Zdroj: PLoS ONE
PLoS ONE, Vol 14, Iss 8, p e0221176 (2019)
ISSN: 1932-6203
Popis: The energy expenditure and substrate utilisation were measured in 5 men pre- and post- a 67 day, 1750km unassisted Antarctic traverse from the Hercules Inlet to the Ross Sea Ice via the South pole pulling sledges weighing 120kg whilst experiencing temperatures as low as -57°C. A 36-hours protocol in a whole body calorimeter was employed to measure periods of rest, sleep and three periods of standardised stepping exercises at 80, 100 and 120 steps min-1; participants were fed isocalorically. Unlike previous expeditions where large weight loss was reported, only a modest loss of body weight (7%, P = 0.03) was found; fat tissue was reduced by 53% (P = 0.03) together with a small, but not statistically significant, increase in lean tissue weight (P = 0.18). This loss occurred despite a high-energy intake (6500 kcal/day) designed to match energy expenditure. An energy balance analysis suggested the loss in body weight could be due to the energy requirements of thermoregulation. Differences in energy expenditure [4.9 (0.1) vs 4.5 (0.1) kcal/min. P = 0.03], carbohydrate utilisation [450 (180) vs 569 (195) g/day; P = 0.03] and lipid utilisation [450 (61) vs 388 (127) g/day, P = 0.03] at low levels of exertion were different from pre-expedition values. Only carbohydrate utilisation remained statistically significant when normalised to body weight. The differences in energy expenditure and substrate utilisation between the pre- and post-expedition for other physiological states (sleeping, resting, higher levels of exercise, etc) were small and not statistically significant. Whilst inter-subject variability was large, there was a tendency for increased carbohydrate utilisation, post-expedition, when fasted that decreased upon feeding.
Databáze: OpenAIRE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje