Bone Marrow: Orchestrated Cells, Cytokines, and Growth Factors for Bone Regeneration
| Autor: | Muna Soltan, Jennifer H. Choi, Dennis Smiler |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Bone Regeneration
medicine.medical_treatment Bone Marrow Cells Bone healing Hematopoietic stem cell transplantation Osteocytes Iliac crest Bone remodeling Bone Marrow Bone cell Adipocytes medicine Humans Growth Substances Bone regeneration Bone Marrow Transplantation Bone Transplantation Chemistry Cell growth Hematopoietic Stem Cell Transplantation Endothelial Cells Mesenchymal Stem Cells Fibroblasts Hematopoietic Stem Cells Cell biology Adult Stem Cells medicine.anatomical_structure Cytokines Bone marrow Stromal Cells Oral Surgery |
| Zdroj: | Implant Dentistry. 18:132-141 |
| ISSN: | 1056-6163 |
| DOI: | 10.1097/id.0b013e3181990e75 |
| Popis: | Bone regeneration requires an orchestrated interaction between various cells and other biological components. The synthesis of bone matrix with the release of cellular cytokines and growth factors facilitates and regulates cell growth. This leads to the maturation of bone that can support functional implants. Bone-marrow aspirate is a rich source of cells, cytokines, and growth factors needed for bone formation. Harvesting the marrow from the anterior iliac crest is a simple, safe, and cost-effective procedure. Mixing it with a resorbable scaffold and transplanting it to a site can predictably enhance bone regeneration. This article explores the anatomy of the bone marrow and describes the necessary elements for successful bone grafts, such as cells, bone matrix, and cellular regulators (both soluble and insoluble). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|