Neuron-specific enolase reduction in irradiated salivary glands of the rat — An immunohistochemical study
| Autor: | Masahiko Mori, Kazuhiko Saitoh, Masaki Toyooka, Mayuko Kunikata, Junji Hashimoto, Kuniya Fujita |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Male
endocrine system Pathology medicine.medical_specialty Histology Submandibular Gland Enolase Salivary Glands Sublingual Gland stomatognathic system medicine Animals Irradiation Salivary gland Chemistry Rats Inbred Strains Striated duct Cell Biology General Medicine Immunohistochemistry Submandibular gland Rats Staining medicine.anatomical_structure Convoluted tubule nervous system Phosphopyruvate Hydratase |
| Zdroj: | Acta Histochemica. 93:277-281 |
| ISSN: | 0065-1281 |
| DOI: | 10.1016/s0065-1281(11)80223-0 |
| Popis: | Summary Neuron-specific enolase ( NSE ) in the salivary glands of normal and irradiated rats was studied by immunohistochemical methods. The normal salivary gland of Sprague-Dawley rats (465 g) showed positive staining for NSE in striated ducts and granular convoluted tubule ( GCT ) cells. A single radiation, TDF (time, dose, fractionation factor) 100 and 200 (18.82 Gy and 27.97 Gy, respectively) was done, and 4 groups (1, 2, 3 and 4 weeks after radiation) of 5 rats each were used. Irradiated salivary glands indicated a remarkable reduction of NSE staining in GCT cells and a reduction but to a lesser degree in the striated duct of the submandibular gland. Immunohistochemical deposition of NSE was not changed in the sublingual glands of irradiated rats. The reduction of NSE immunodeposition was irradiation dose dependent. |
| Databáze: | OpenAIRE |
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