Recommendations for the measurement of sexual steroids in clinical practice. A position statement of SEQCML/SEEN/SEEP

Autor: Gregori Casals, Roser Ferrer Costa, Eulàlia Urgell Rull, Héctor F. Escobar-Morreale, Jesús Argente, Gemma Sesmilo, Betina Biagetti
Přispěvatelé: Institut Català de la Salut, [Casals G] Servicio de Bioquímica y Genética Molecular, Hospital Clínic, IDIBAPS, CIBEREHD Universidad de Barcelona, Barcelona, Spain. [Ferrer Costa R] Servei de Bioquímica Clínica, Vall d'Hebron Hospital Universitari, Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. [Urgell Rull E] Servicio de Bioquímica, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain. [Escobar-Morreale HF] Servicio de Endocrinología y Nutrición, Hospital Ramón y Cajal, Universidad de Alcalá, Instituto Ramón y Cajal de Investigación Sanitaria IRYCIS y CIBER Diabetes y Enfermedades Metabólicas Asociadas CIBERDEM, Madrid, Spain. [Argente J] Departamento de Pediatría y Endocrinología Pediátrica, Hospital Infantil Universitario Niño Jesús, Universidad Autonoma de Madrid, CIBEROBN, Instituto de Salud Carlos III, Madrid, Spain. [Sesmilo G] Servicio de Endocrinología y Nutrición, Hospital Universitari Dexeus, Barcelona, Spain. [Biagetti B] Servei d’Endocrinologia i Nutrició, Vall d'Hebron Hospital Universitari, Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain, Vall d'Hebron Barcelona Hospital Campus
Rok vydání: 2023
Předmět:
Zdroj: Scientia
ISSN: 2628-491X
Popis: Immunoassay; Sexual steroids; Testosterone Immunoassaig; Esteroides sexuals; Testosterona Inmunoensayo; Esteroides sexuales; Testosterona The proper clinical approach to a wide range of disorders relies on the availability of accurate, reproducible laboratory results for sexual steroids measured using methods with a high specificity and sensitivity. The chemiluminescent immunoassays currently available have analytical limitations with significant clinical implications. This position statement reviews the current limitations of laboratory techniques for the measurement of estradiol and testosterone and their impact on diverse clinical scenarios. A set of recommendations are provided to incorporate steroid hormone analysis by mass spectrometry in national health systems. International societies have recommended this methodology for a decade.
Databáze: OpenAIRE