New insights into the cardiovascular risk of migraine and the role of white matter hyperintensities: is gold all that glitters?
| Autor: | Raffaele Costantini, Paolo Martelletti, Alessandra Fabrizio, Andrea Mezzetti, Giannapia Affaitati, Emmanuele Tafuri, Maria Adele Giamberardino, Andrea Negro, Marco Tana, Claudio Tana |
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| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
Neurology Migraine Disorders Clinical Neurology Review Article Nerve Fibers Myelinated Cardiovascular events Insulin resistance Internal medicine medicine Humans Risk factor Psychiatry Migraine cardiovascular events migraine risk factors Framingham Risk Score business.industry Brain General Medicine medicine.disease Migraine with aura Hyperintensity Anesthesiology and Pain Medicine Risk factors Cardiovascular Diseases Neurology (clinical) medicine.symptom Metabolic syndrome business |
| Zdroj: | The Journal of Headache and Pain |
| ISSN: | 1129-2377 1129-2369 |
| DOI: | 10.1186/1129-2377-14-9 |
| Popis: | The role of migraine as an independent risk factor for cardiovascular events has been debated for several years, while it is more established for ischemic stroke. Recently, new studies have examined the likelihood of migraine to determine cardiovascular events, supporting the hypothesis of a predominant role in patients with migraine with aura, the risk including both sexes. In the literature, multiple pathophysiological mechanisms are described to explain this association, and are here discussed. Furthermore, the emerging evidence that a higher headache frequency and long-term migraine may worsen the cardio-metabolic profile in migraineurs (e.g. with a higher Framingham risk score and risk of developing atherosclerosis, insulin resistance and metabolic syndrome) makes it increasingly necessary to reduce the number and severity of attacks, not only to alleviate the painful symptoms, but also to improve the prognosis in these patients. |
| Databáze: | OpenAIRE |
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