Nitinol Stent Implantation Versus Percutaneous Transluminal Angioplasty in Superficial Femoral Artery Lesions up to 10 cm in Length
| Autor: | Bernhard Reimers, Thomas Zeller, Thilo Tübler, Marc Bosiers, Karl-Ludwig Schulte, Karlheinz Bürgelin, Hermann J. Steinkamp, Gunnar Tepe, Patrick Peeters, Hans Krankenberg, Dierk Scheinert, Felix Mahler, Erich Minar, Michael Schlüter |
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| Rok vydání: | 2007 |
| Předmět: |
Male
Nitinol stent medicine.medical_specialty Percutaneous medicine.medical_treatment Femoral artery Blood Vessel Prosthesis Implantation Restenosis Ischemia Physiology (medical) medicine.artery Angioplasty Alloys Humans Medicine Aged Ultrasonography business.industry Vascular disease Superficial femoral artery Graft Occlusion Vascular Stent Middle Aged medicine.disease Surgery Femoral Artery Female Stents Radiology Cardiology and Cardiovascular Medicine business Angioplasty Balloon |
| Zdroj: | Circulation. 116:285-292 |
| ISSN: | 1524-4539 0009-7322 |
| DOI: | 10.1161/circulationaha.107.689141 |
| Popis: | Background— Endoluminal treatment of superficial femoral artery lesions is a matter of controversy. The present study was designed to investigate the impact of nitinol stenting of superficial femoral artery lesions with a maximum length of 10 cm on restenosis and clinical outcomes at 1 year. Methods and Results— Two hundred forty-four patients (168 men; 66±9 years) with a single superficial femoral artery lesion and chronic limb ischemia were randomized to implantation of a single Bard Luminexx 3 stent (123 patients) or stand-alone percutaneous transluminal angioplasty (PTA) (121 patients). Mean lesion length was 45 mm. Technical success (residual stenosis P =0.377). Target lesion revascularization rates at 1 year were 18.3% and 14.9%, respectively (absolute treatment difference, −3.3%; 95% CI, −13.0% to 6.4%; P =0.595). No statistically significant difference between treatment groups was observed at 12 months in the improvement by at least 1 Rutherford category of peripheral arterial disease. Conclusions— In the present study of patients with short superficial femoral artery lesions, the hypothesized absolute difference of 20% in binary restenosis at 1 year between the implantation of a single Luminexx nitinol stent and stand-alone PTA could not be demonstrated. A smaller difference requiring a larger trial might have been missed. |
| Databáze: | OpenAIRE |
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