Shape-dependent antibacterial activity of silver nanoparticles on Escherichia coli and Enterococcus faecium bacterium
| Autor: | R. B. M. Cross, A. Alshareef, Katie Laird |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Materials science
Microorganism General Physics and Astronomy Nanotechnology 02 engineering and technology 010402 general chemistry medicine.disease_cause 01 natural sciences Silver nanoparticle Antibiotic resistance antibacterial activity shape-dependent medicine Escherichia coli biology Surfaces and Interfaces General Chemistry 021001 nanoscience & nanotechnology Condensed Matter Physics Antimicrobial biology.organism_classification Enterococcus sp 0104 chemical sciences Surfaces Coatings and Films AgNPs E.coli 0210 nano-technology Antibacterial activity Bacteria Nuclear chemistry Enterococcus faecium |
| Zdroj: | Applied Surface Science. 424:310-315 |
| ISSN: | 0169-4332 |
| DOI: | 10.1016/j.apsusc.2017.03.176 |
| Popis: | The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link. Silver nanoparticles (AgNPs) have been shown to exhibit strong antibacterial activity against both Gram-positive bacteria and Gram-negative bacteria including antibiotic resistant strains. The antibacterial activity of AgNPs against Escherichia coli and Streptococcus mutans (S. Mutans) has been reported and found to be size dependent. This study aims to compare the bactericidal effect of different shaped AgNPs (spherical and truncated octahedral) against E.coli and E.faecium. The antimicrobial activity of a range of concentrations (50, 100, 1000μg/ml) was determined over 24 hours using both optical density and viable counts. Truncated octahedral AgNPs (AgNoct) were found to be more active when compared with spherical AgNPs (AgNS). The difference in shape resulted in differences in efficacy which may be due to the higher surface area of AgNOct compared to AgNS, and differences in active facets and surface energies, with AgNPs having a bacteriostatic effect and AgNOct is being bactericidal after 4 hours. The results suggest that AgNPs can be used as effective growth inhibitors in different microorganisms, rendering them applicable tovarious medical devices and antimicrobial control systems. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect