Movement compensation during carbon dioxide coronary angiography: In-vitro validation
| Autor: | Edoardo Pirazzini, Nevio Taglieri, Ivan Corazza, Romano Zannoli, James G. Caridi, Alessandro Lombi, Sonia Sapignoli, Pier Luca Rossi |
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| Přispěvatelé: | Corazza, Ivan, Sapignoli, Sonia, Rossi, Pier Luca, Lombi, Alessandro, Pirazzini, Edoardo, Taglieri, Nevio, Caridi, James G., Zannoli, Romano |
| Rok vydání: | 2018 |
| Předmět: |
Coronary angiography
medicine.medical_specialty Aorta business.industry CO2 angiography coronary arteries contrast-induced nephropathies cerebral ischemia movement compensation Diastole General Physics and Astronomy 030204 cardiovascular system & hematology lcsh:QC1-999 030218 nuclear medicine & medical imaging Compensation (engineering) Coronary arteries 03 medical and health sciences Cerebral circulation Coronary circulation Contrast medium 0302 clinical medicine medicine.anatomical_structure Internal medicine medicine.artery medicine Cardiology business lcsh:Physics |
| Zdroj: | AIP Advances, Vol 8, Iss 9, Pp 095005-095005-7 (2018) |
| ISSN: | 2158-3226 |
| DOI: | 10.1063/1.5030796 |
| Popis: | The aim of this in vitro study was to evaluate the feasibility of movement compensation for CO2 coronary angiography. The use of CO2 as a contrast medium for coronary angiography in a routine clinical setting is still premature. Nonetheless, the gas can solve most of the problems related to iodine contrast-induced nephropathy and can be safely used for patients with renal insufficiency. In a previous work [I. Corazza et al., AIP Adv. 8(1), 015225 (2018)], we demonstrated that an adequate setting of the CO2 injection parameters (pressures and volumes) allows gas injection into the coronaries, avoiding reflux into the aorta and cerebral circulation. A mechanical mock simulating coronary circulation and movement was used to simulate different CO2 injection conditions. Simultaneous acquisition of ECG and optical images allowed synchronous frame extraction for post-processing analysis, like masking and stacking processes. A single test with a radiological apparatus was done to demonstrate the feasibility of the technique. By injecting CO2 at a pressure between the dicrotic notch and diastolic value, no reflux into the aorta was observed and the new software yielded final optical images of clinical quality after about 8 seconds of injection. The feasibility test under the X-ray apparatus gave promising results. CO2 coronary angiography is still far from becoming a clinical standard, but our bench evaluation demonstrates that if the injection parameters are well-controlled and physiological values known, CO2 can be used as a contrast agent not only for the lower part of the body, but also for the coronary arteries, respecting basic safety standards.The aim of this in vitro study was to evaluate the feasibility of movement compensation for CO2 coronary angiography. The use of CO2 as a contrast medium for coronary angiography in a routine clinical setting is still premature. Nonetheless, the gas can solve most of the problems related to iodine contrast-induced nephropathy and can be safely used for patients with renal insufficiency. In a previous work [I. Corazza et al., AIP Adv. 8(1), 015225 (2018)], we demonstrated that an adequate setting of the CO2 injection parameters (pressures and volumes) allows gas injection into the coronaries, avoiding reflux into the aorta and cerebral circulation. A mechanical mock simulating coronary circulation and movement was used to simulate different CO2 injection conditions. Simultaneous acquisition of ECG and optical images allowed synchronous frame extraction for post-processing analysis, like masking and stacking processes. A single test with a radiological apparatus was done to demonstrate the feasibility of th... |
| Databáze: | OpenAIRE |
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