Human rhinoviruses in otitis media with effusion

Autor: M. Xatzipsalti, Andreas Constantopoulos, T. Bairamis, F. M. Chantzi, Dimitris A. Kafetzis, G. Liapi, M. Tsiakou, N. Bournousouzis, Nikolaos G. Papadopoulos
Rok vydání: 2006
Předmět:
Zdroj: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology. 17(7)
ISSN: 0905-6157
Popis: Frequent viral upper respiratory tract infections (URTI) are considered to be risk factors for otitis media with effusion (OME). Atopy has also been associated with both OME and viral infections. The aim of this study was to evaluate the presence of viruses in middle ear effusions (MEE) in children 2-7 yr old with OME, and to determine risk factors for virus detection in the MEE. MEE samples, collected at the time of myringotomy from 37 children with OME were assessed. Physical examination, skin prick tests and a standardized questionnaire on OME and allergy were also performed. Viral RNA was detected by the use of reverse transcription PCR (RT-PCR). Fifteen samples (40.5%) were positive for rhinovirus (RV). One enterovirus and no other respiratory viruses were detected. Two out of five (40%), 3/7 (43%) and 10/25 (40%) were positive for RV in acute, subacute and chronic cases, respectively. Children with frequent episodes of OM, with early onset of OM (
Databáze: OpenAIRE