Male factors in ART outcome prediction
| Autor: | Jean Calleja-Agius, Sarah Catania, Pierre Schembri Wismayer, Dale Brincat |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Anti-Mullerian Hormone
Male medicine.medical_specialty Pregnancy Rate Reproductive Techniques Assisted Homocysteine Endocrinology Diabetes and Metabolism medicine.medical_treatment media_common.quotation_subject DNA Fragmentation Biology Male infertility chemistry.chemical_compound Folic Acid Endocrinology Pregnancy medicine Humans Infertility Male media_common Gynecology Assisted reproductive technology In vitro fertilisation Obstetrics Obstetrics and Gynecology Prognosis medicine.disease Spermatozoa Treatment Outcome chemistry Female Reproduction Reactive Oxygen Species Outcome prediction Body mass index Biomarkers |
| Zdroj: | Gynecological Endocrinology. 31:169-175 |
| ISSN: | 1473-0766 0951-3590 |
| DOI: | 10.3109/09513590.2014.984678 |
| Popis: | Paternal influences on reproduction are significant causing about half of the infertile couples to turn to assisted reproductive techniques. Due to the increasing proportion of infertile couples adopting to conceive by in vitro fertilisation (IVF), predicting outcomes is of ever increasing importance. Since pregnancy rates following IVF are still quite low, prognostic information is very helpful in clinical decisions. Although significant research has been done on the maternal influence, male factor infertility is relatively understudied. To date, potential predictors include: method of fertilisation, age, reactive oxygen species, sperm quality parameters and DNA fragmentation. Predictors under investigation which show promising signs, even though there is no clear cut consensus on the predictive value to date include: folate and homocysteine, anti müllerian hormone measurement, environmental factors, body mass index, smoking, male age, stress, some subsets of antisperm antibodies and epigenetic features. |
| Databáze: | OpenAIRE |
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