Long-term Study of Lyme Borreliosis in a Highly Endemic Area in Sweden
Autor: | Johan Berglund, S R Norrby, R Eitrem |
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Rok vydání: | 1996 |
Předmět: |
Adult
Male Microbiology (medical) medicine.medical_specialty Adolescent Endemic Diseases Enzyme-Linked Immunosorbent Assay Spirochaetaceae Serology Lyme disease Borrelia burgdorferi Group Seroepidemiologic Studies Surveys and Questionnaires Epidemiology Humans Medicine Longitudinal Studies Prospective Studies Borrelia burgdorferi Child Aged Aged 80 and over Sweden Lyme Disease General Immunology and Microbiology biology business.industry Incidence Incidence (epidemiology) Infant General Medicine Middle Aged bacterial infections and mycoses medicine.disease biology.organism_classification Antibodies Bacterial Infectious Diseases Immunoglobulin M Child Preschool Immunoglobulin G Immunology biology.protein Erythema migrans Female business |
Zdroj: | Scandinavian Journal of Infectious Diseases. 28:473-478 |
ISSN: | 1651-1980 0036-5548 |
DOI: | 10.3109/00365549609037943 |
Popis: | From May 1991 to May 1994, Lyme borreliosis was studied prospectively in 301 residents living on Aspö, a highly endemic area for the disease. The study included annual questionnaires and blood samples for serology. Immunoglobulin G (IgG) antibodies to Borrelia burgdorferi sensu lato were detected by enzyme-linked immunosorbent assay in 63/301 (21%) of the residents at the start of the study. Seropositivity rates increased with time, and 3 years later 101/301 (34%) were positive. A total of 34 individuals developed physician-verified manifestations of Lyme borreliosis during the study period. Nine individuals developed an erythema migrans, despite a previously treated Lyme borreliosis or pre-existing high levels of IgG antibodies to B. burgdorferi s.l. |
Databáze: | OpenAIRE |
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