A structured exercise program for patients with advanced non-small cell lung cancer
| Autor: | Joseph A. Greer, Jennifer S. Temel, Matthew R. Smith, Thomas J. Lynch, Paula Downes Vogel, David C. Christiani, William F. Pirl, Michael B. Sullivan, Sarah B. Goldberg |
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| Rok vydání: | 2009 |
| Předmět: |
Pulmonary and Respiratory Medicine
Male medicine.medical_specialty Lung Neoplasms Strength training Population Article 03 medical and health sciences 0302 clinical medicine Non-small cell lung cancer Quality of life Carcinoma Non-Small-Cell Lung Surveys and Questionnaires medicine Clinical endpoint Carcinoma Aerobic exercise Humans 030212 general & internal medicine Lung cancer education Exercise Aged Aged 80 and over education.field_of_study business.industry Cancer Middle Aged medicine.disease 3. Good health Exercise Therapy Treatment Outcome Oncology 030220 oncology & carcinogenesis Physical therapy Quality of Life Feasibility Studies Female business Supportive care |
| Zdroj: | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 4(5) |
| ISSN: | 1556-1380 |
| Popis: | Introduction: Exercise improves functional outcome and symptoms for certain cancer populations, but the feasibility, efficacy, and safety of structured exercise in patients with lung cancer is unknown. In this study, we examined the feasibility of a hospital-based exercise program for patients with advanced non-small cell lung cancer. Methods: This study included patients with newly diagnosed advanced stage non-small cell lung cancer and Eastern Cooperative Oncology Group performance status 0–1. A physical therapist facilitated twice-weekly sessions of aerobic exercise and weight training over an 8-week period. The primary end point was feasibility of the intervention, defined as adherence to the exercise program. Secondary endpoints included functional capacity, measured by the 6-minute walk test and muscle strength, as well as quality of life, lung cancer symptoms and fatigue, measured by the Functional Assessment of Cancer Therapy-lung and Functional Assessment of Cancer Therapy-fatigue scales. Results: Between October 2004 and August 2007, 25 patients enrolled in the study. All participants received anticancer therapy during the study period. Twenty patients (80%) underwent the baseline physical therapy evaluation. Eleven patients (44%) completed all 16 sessions. An additional 6 patients attended at least 6 sessions (range, 6–15), and 2 patients only attended one session. Study completers experienced a significant reduction in lung cancer symptoms and no deterioration in their 6-minute walk test or muscle strength. Conclusions: Although the majority of participants attempted the exercise program, less than half were able to complete the intervention. Those who completed the program experienced an improvement in their lung cancer symptoms. Community-based or briefer exercise interventions may be more feasible in this population. |
| Databáze: | OpenAIRE |
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