Osteoporosis detection by 3T diffusion tensor imaging and MRI spectroscopy in women older than 60 years
| Autor: | Gme Simonetti, Umberto Tarantino, Ezio Fanucci, Armando Fusco, Guglielmo Manenti, Silvia Capuani |
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| Rok vydání: | 2013 |
| Předmět: |
In vivo magnetic resonance spectroscopy
Aging Magnetic Resonance Spectroscopy Osteoporosis Sensitivity and Specificity Body Mass Index Settore MED/36 - Diagnostica per Immagini e Radioterapia Fractional anisotropy medicine Humans Aged Fat fraction Femoral neck Aged 80 and over Femur Neck business.industry Healthy subjects Water Middle Aged medicine.disease Healthy Volunteers Postmenopause Bone Diseases Metabolic Diffusion Tensor Imaging medicine.anatomical_structure Anisotropy Female Protons Geriatrics and Gerontology business Nuclear medicine Cancellous bone Diffusion MRI |
| Zdroj: | Aging Clinical and Experimental Research (Online) (2013). info:cnr-pdr/source/autori:Manenti, G [ 1 ] ; Capuani, S [ 1][2 ] ; Fusco, A [ 1 ] ; Fanucci, E [ 1 ] ; Tarantino, U [ 1 ] ; Simonetti, G [ 1 ]/titolo:Osteoporosis detection by 3T diffusion tensor imaging and MRI spectroscopy in women older than 60 years/doi:/rivista:Aging Clinical and Experimental Research (Online)/anno:2013/pagina_da:/pagina_a:/intervallo_pagine:/volume |
| ISSN: | 1720-8319 |
| DOI: | 10.1007/s40520-013-0091-0 |
| Popis: | Aim of this study was to evaluate the cancellous bone quality of postmenopausal women (age >60 years) by diffusion tensor imaging (DTI) using mean diffusivity (MD) and fractional anisotropy (FA) in combination with proton magnetic resonance spectroscopy (1H-MRS). 20 postmenopausal women older than 60 years were introduced to dual-energy X-ray absorptiometry (DXA) examination in femoral neck and to an MRI spectroscopy and DTI evaluation at 3T. We observed that fat fraction (FF) can discriminate healthy and osteoporotic patients. Water mean diffusivity (MD) and FA can discriminate the healthy group from osteopenic and osteoporotic group. MD/FF vs FA/FF graph extracted from the femoral neck identifies all healthy individuals, according to DXA results. DTI and spectroscopy protocol performed in the femoral neck could be highly sensitive and specific in identifying healthy subjects. |
| Databáze: | OpenAIRE |
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