Artefacts in oral incisional biopsies in general dental practice: a pathology audit

Autor: Pablo Varela-Centelles, M.A. Romero, Juan Seoane, J.R. Ramirez, J Cameselle-Teijeiro
Rok vydání: 2004
Předmět:
Zdroj: Oral Diseases. 10:113-117
ISSN: 1601-0825
1354-523X
DOI: 10.1111/j.1354-523x.2003.00983.x
Popis: Objectives: To investigate the artefacts in oral biopsies taken by general dental practitioners (GDP) and oral and maxillofacial surgeons (O&MF) and to assess the concordance of clinical and pathological diagnoses. Design: Cross-sectional investigation. Setting: Primary care and hospital practice. Material and methods: A total of 354 randomly selected oral biopsy samples studied by the same pathologist. Main outcome measures: Clinical and pathological diagnoses – prevalence and location of surgical handling artefacts: crush, splits, haemorrhage and fragmentation. Results: Artefacts identified in GDPs biopsies: crush 27.1%; haemorrhage 19.8%; splits 11.3%; and fragmentation 6.2%. OM splits 13%; fragmentation 2.3%; and haemorrhage 8.5%. No differences in split or fragmentation were identified between GDPs and OM P = 0.000) and haemorrhage (χ2 = 9.31; P = 0.003) were more frequently identified in GDPs biopsies. Concordance between clinical and pathological diagnoses was excellent ( > 0.75) for both groups in all disorders considered. Conclusions: The elicited clinical knowledge, the quality of the samples sent to the pathologists seem to suggest the advisability for the GDPs to perform diagnostic biopsies.
Databáze: OpenAIRE