Cardiovascular risk factor(s) prevalence in Greek hypertensives. Effect of gender and age
| Autor: | P G Spanos, Charalampos I. Liakos, S-M G Kyvelou, Andreas P. Michaelides, Vanessa Tzamou, C. Stefanadis, Gregory P. Vyssoulis, E. Karpanou, Areti Triantafyllou |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Male medicine.medical_specialty Left ventricular hypertrophy Sex Factors Risk Factors Internal medicine Prevalence Internal Medicine medicine Humans Risk factor HeartScore Aged Retrospective Studies Aged 80 and over Framingham Risk Score Greece medicine.diagnostic_test business.industry Smoking Age Factors Absolute risk reduction Middle Aged medicine.disease Endocrinology Cardiovascular Diseases Cardiology Female Metabolic syndrome business Lipid profile Dyslipidemia Glomerular Filtration Rate |
| Zdroj: | Journal of Human Hypertension. 26:443-451 |
| ISSN: | 1476-5527 0950-9240 |
| DOI: | 10.1038/jhh.2011.55 |
| Popis: | The aim of this study was to determine cardiovascular (CV) risk factors (RFs) and target organ damage clustering in 21280 Greek hypertensives stratified by gender and age. Glycemic and lipid profile were determined, left ventricular mass index, estimated gromerular filtration rate (eGFR), 10-years CV risk according to Framingham risk score (FRS) and HeartScore (HS) were calculated. Only 10.2% of patients had no concomitant RFs, 53.1% had one (48.8% dyslipidemia, 3.4% smoking, 0.9% diabetes), 32.9% had two (26% dyslipidemia and smoking, 6.6% dyslipidemia and diabetes, 0.3% smoking and diabetes) and 3.7% had all four traditional RFs. Obesity was present in 30%, metabolic syndrome in 38%, low eGFR in 24% and left ventricular hypertrophy in 49%. Mean FRS risk was 35% for males, 24.1% for females whereas in high risk (20%) were 68.7 and 50.7%, respectively (P0.0001). Mean HS risk was 8.4% for males, 6.2% for females whereas in high risk (5%) were 48.6 and 36.2%, respectively (P0.0001). Age was correlated to pulse pressure, eGFR, left ventricular mass index and CV risk (P0.0001). Ageing increased the risk difference between genders for total (P=0.001) but not for fatal events (P=nonsignificant). In conclusion, as RFs cluster in hypertensives, CV risk calculation should guide treatment decisions. |
| Databáze: | OpenAIRE |
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