Synchronous diagnosis of multiple tumours in a postmenopausal woman
| Autor: | Joaquin J. Nieto, Joe Ostrowski, Nikolaos Burbos, Ilias Giarenis, Ray Lonsdale |
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| Rok vydání: | 2009 |
| Předmět: |
Adenoma
medicine.medical_specialty Pathology Genital Neoplasms Female Partial Omentectomy Adenocarcinoma Anastomosis Liposarcoma Palpation Neoplasms Multiple Primary medicine Humans Vaginal bleeding Retroperitoneal Neoplasms Aged medicine.diagnostic_test business.industry Obstetrics and Gynecology General Medicine medicine.disease Postmenopause Colonic Neoplasms Female Histopathology medicine.symptom business |
| Zdroj: | Archives of Gynecology and Obstetrics. 280:627-630 |
| ISSN: | 1432-0711 0932-0067 |
| DOI: | 10.1007/s00404-009-0948-9 |
| Popis: | We report an unusual case of a postmenopausal woman that was diagnosed with multiple tumours derived from different embryogenic tissues. She presented with postmenopausal vaginal bleeding. Clinical examination revealed a large pelvic mass, tender on palpation. Serum CA-125 level was elevated at 8,985 kU/l (normal range 0-35). A CT scan showed a malignant-appearing right ovarian mass with a peritoneal nodule, small amount of free fluid in the pelvis and evidence of a colonic intussusception. The patient underwent total abdominal hysterectomy, bilateral salpingo-ophorectomy, partial omentectomy and right hemicolectomy with side-to-side anastomosis. Histopathology showed a Grade 3 endometrial adenocarcinoma. Both ovaries were completely replaced by partially necrotic poorly differentiated endometrioid adenocarcinoma. Small deposits of metastatic adenocarcinoma were seen within the omentum. Sections from the retroperitoneal mass showed a low-grade liposarcoma. A large polypoid tumour within the right colon was a tubulo-villous adenoma. |
| Databáze: | OpenAIRE |
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