Temperature in mice after ethanol: Effect of probing and regain of righting reflex
| Autor: | Christine L. Melchior, Pamela M. Allen |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Male
Health (social science) medicine.drug_class Posture Toxicology Biochemistry Body Temperature Hypnotic Mice Behavioral Neuroscience chemistry.chemical_compound Stress Physiological Reflex medicine Animals Motor activity Postural Balance Ethanol effect Ethanol Chemistry General Medicine Thermoregulation Mice Inbred C57BL Heat conservation Neurology Anesthesia Biophysics Righting reflex Falling (sensation) Body Temperature Regulation |
| Zdroj: | Alcohol. 10:17-20 |
| ISSN: | 0741-8329 |
| DOI: | 10.1016/0741-8329(93)90048-s |
| Popis: | The handling involved in rectally probing a mouse in order to measure body temperature is a stress which results in an increase in body temperature. However, after an injection of ethanol the fall in body temperature caused by ethanol is exacerbated by probing. In mice, decreases in temperature following probing are ethanoldose dependent and can be generated on both the falling and rising phases of the ethanol induced change in temperature. The effect of probing can be observed when the mice are under the hypnotic influence of ethanol, and regain of righting reflex itself is followed by a fall in temperature. The resumption of motor activity in undisturbed mice following an hypnotic dose of ethanol also is accompanied by a fall in temperature. Therefore, the drop in temperature observed in any of these procedures which involve moving the mice may be attributable to the disruption of heat conservation rather than a stress interaction. |
| Databáze: | OpenAIRE |
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