Pneumocystis jirovecii pneumonia in solid organ transplant recipients: a descriptive analysis for the Swiss Transplant Cohort

Autor:	Neofytos, Dionysios, Hirzel, Cédric, Boely, Elsa, Lecompte, Thanh, Khanna, Nina, Mueller, Nicolas J, Boggian, Katia, Cusini, Alexia, Manuel, Oriol, Banz Wüthrich, Vanessa, Beldi, Guido, Stirnimann, Guido, van Delden, Christian, Swiss Transplant, Cohort Study
Přispěvatelé:	Swiss Transplant Cohort Study, Amico, P., Aubert, J.D., Banz, V., Beldi, G., Benden, C., Berger, C., Binet, I., Bochud, P.Y., Boëly, E., Bucher, H., Carell, T., Catana, E., Chalandon, Y., de Geest, S., de Rougemont, O., Dickenmann, M., Duchosal, M., Elkrief, L., Fehr, T., Ferrari-Lacraz, S., Garzoni, C., Soccal, P.G., Gaudet, C., Giostra, E., Golshayan, D., Hadaya, K., Halter, J., Heim, D., Hess, C., Hillinger, S., Hirsch, H.H., Hofbauer, G., Huynh-Do, U., Immer, F., Klaghofer, R., Koller, M., Laesser, B., Lehmann, R., Lovis, C., Majno, P., Marti, H.P., Martin, P.Y., Meylan, P., Mohacsi, P., Morel, P., Mueller, U., Mueller-McKenna, H., Müller, A., Müller, T., Müllhaupt, B., Pascual, M., Passweg, J., Posfay-Barbe, K., Rick, J., Roosnek, E., Rosselet, A., Rothlin, S., Ruschitzka, F., Schanz, U., Schaub, S., Schnyder, A., Seiler, C., Sprachta, J., Stampf, S., Steiger, J., Stirnimann, G., Toso, C., Venetz, J.P., Villard, J., Wick, M., Wilhelm, M., Yerly, P., University of Zurich, Neofytos, Dionysios
Rok vydání:	2018
Předmět:	0301 basic medicine Male Epidemiology 2747 Transplantation Pneumocystis carinii Adult Aged Anti-Bacterial Agents/therapeutic use Antibiotic Prophylaxis/methods Antibiotic Prophylaxis/standards Female Humans Incidence Middle Aged Mortality Organ Transplantation/adverse effects Pneumocystis carinii/isolation & purification Pneumonia Pneumocystis/drug therapy Pneumonia Pneumocystis/epidemiology Pneumonia Pneumocystis/microbiology Pneumonia Pneumocystis/prevention & control Practice Guidelines as Topic Prospective Studies Switzerland/epidemiology Treatment Outcome Trimethoprim Sulfamethoxazole Drug Combination/therapeutic use Young Adult Pneumocystis jirovecii pneumonia Solid organ transplant recipients 10234 Clinic for Infectious Diseases 0302 clinical medicine 030212 general & internal medicine Prospective cohort study 610 Medicine & health education.field_of_study ddc:617 Incidence (epidemiology) Pneumonia Pneumocystis Anti-Bacterial Agents Infectious Diseases 10219 Clinic for Gastroenterology and Hepatology Cohort 10209 Clinic for Cardiology 10178 Clinic for Pneumology Switzerland medicine.drug medicine.medical_specialty 030106 microbiology Population 03 medical and health sciences Internal medicine parasitic diseases Trimethoprim Sulfamethoxazole Drug Combination medicine education Transplantation business.industry 2725 Infectious Diseases Organ Transplantation Antibiotic Prophylaxis medicine.disease Trimethoprim Pneumonia Complication business
Zdroj:	Transplant infectious disease, vol. 20, no. 6, pp. e12984 Neofytos, Dionysios; Hirzel, Cédric; Boely, Elsa; Lecompte, Thanh; Khanna, Nina; Mueller, Nicolas J; Boggian, Katia; Cusini, Alexia; Manuel, Oriol; Banz Wüthrich, Vanessa; Beldi, Guido; Stirnimann, Guido; van Delden, Christian; Swiss Transplant, Cohort Study (2018). Pneumocystis jirovecii pneumonia in solid organ transplant recipients: a descriptive analysis for the Swiss Transplant Cohort. Transplant infectious disease, 20(6), e12984. Wiley 10.1111/tid.12984 Transplant Infectious Disease, Vol. 20, No 6 (2018) P. e12984
ISSN:	1399-3062 1398-2273
Popis:	BACKGROUND Descriptive data on Pneumocystis jirovecii pneumonia (PJP) in solid organ transplant recipients (SOTr) in the era of routine Pneumocystis-prophylaxis are lacking. METHODS All adult SOTr between 2008-2016 were included. PJP was diagnosed based on consensus guidelines. Early-onset PJP was defined as PJP within the 1st-year-post-transplant. RESULTS 41/2842 SOTr (1.4%) developed PJP (incidence rate: 0.01/1000 person-days) at a mean of 493-days post-transplant: 21 (51.2%) early vs 20 (48.8%) late-onset PJP. 2465 (86.7%) SOTr received Pneumocystis-prophylaxis for a mean 316 days. PJP incidence was 0.001% and 0.003% (log-rank
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aca42e09a97ea21faa3ee90f37d3d899 https://pubmed.ncbi.nlm.nih.gov/30155950 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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