Quantification of liver iron concentration with magnetic resonance imaging by combining T1-, T2-weighted spin echo sequences and a gradient echo sequence
| Autor: | Reint Huizenga, HG Kreeftenberg, EL Mooyaart, Willem Sluiter |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Adult
Male Liver Iron Concentration Cirrhosis Biopsy Iron HEMOCHROMATOSIS DIAGNOSIS DISEASE Internal Medicine medicine Humans magnetic resonance imaging liver iron concentration Hemochromatosis Monitoring Physiologic medicine.diagnostic_test business.industry Transferrin OVERLOAD Magnetic resonance imaging Pulse sequence Reference Standards medicine.disease Liver haemochromatosis THALASSEMIA MAJOR Liver biopsy Ferritins Spin echo Female Nuclear medicine business |
| Zdroj: | Netherlands Journal of Medicine, 56(4), 133-137. van Zuiden Communications BV. |
| ISSN: | 0300-2977 |
| Popis: | Background: The aim of the study was to quantify hepatic iron by MRI for practical use. Methods: In twenty-three patients with various degrees of iron overload, measurements were carried out with a 1.5 Tesla MR unit. A combination of pulse sequences (T1, T2 and gradient echo) enabled us to quantify smaller amounts of liver iron as accurately as larger amounts of liver iron. The gradient echo sequence provided us with a good correlation when detecting smaller amounts of iron in the liver where the T1 sequence provided a good correlation when larger amounts of iron were present. Results: The combination of the three sequences showed a nice correlation (r=−0.93, P |
| Databáze: | OpenAIRE |
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