Chronic fatigue syndrome: the current status and future potentials of emerging biomarkers
| Autor: | Adam C. Strauss, Elizabeth R. Unger, Leonard A. Jason, Arsani William, Gailen D. Marshall, Jordan D. Dimitrakoff, David Fischer |
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| Rok vydání: | 2014 |
| Předmět: |
musculoskeletal diseases
Pathology medicine.medical_specialty Neurology business.industry Public Health Environmental and Occupational Health virus diseases Medicine (miscellaneous) medicine.disease Article nervous system diseases Behavioral Neuroscience Chronic fatigue syndrome Medicine Treatment strategy business Intensive care medicine |
| Zdroj: | Fatigue: Biomedicine, Health & Behavior. 2:93-109 |
| ISSN: | 2164-1862 2164-1846 |
| DOI: | 10.1080/21641846.2014.906066 |
| Popis: | Background: Chronic fatigue syndrome (CFS) remains an incompletely characterized illness, in part due to controversy regarding its definition, biological basis, and diagnosis. Purpose: Biomarkers are objective measures that may lead to improvements in our understanding of CFS by providing a more coherent and consistent approach to study, diagnosis, and treatment of the illness. Such metrics may allow us to distinguish between CFS subtypes – each defined by characteristic biomarkers – currently conflated under the single, heterogeneous condition of CFS. These delineations, in turn, may guide more granular, focused, and targeted treatment strategies based on more precise characterizations of the illness. Methods: Here, we review potential CFS biomarkers related to neurological and immunological components of the illness. Results, Conclusions: We discuss how these biomarkers may be used to move the field of CFS forward, emphasizing clinical utility and potential routes of future research. |
| Databáze: | OpenAIRE |
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