Clinical characteristics and risk factors of tigecycline-associated hypofibrinogenaemia in critically ill patients

Autor:	Xue-Ling Fang, Yong-Hong Xiao, Yang-Xiao Lai, Qiang Fang, Yi Zheng, Juan Hu
Rok vydání:	2020
Předmět:	Adult Male medicine.medical_specialty Coagulation disturbances Critical Illness Hypofibrinogenaemia Cefoperazone Tigecycline Fibrinogen 030226 pharmacology & pharmacy Gastroenterology Sepsis 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine medicine Coagulopathy Humans Pharmacology (medical) 030212 general & internal medicine Aged Retrospective Studies Aged 80 and over Pharmacology Maintenance dose business.industry Bacterial Infections General Medicine Sulbactam Middle Aged Afibrinogenemia medicine.disease Clinical Trial Anti-Bacterial Agents Discontinuation Case-Control Studies Female Blood Coagulation Tests business medicine.drug
Zdroj:	European Journal of Clinical Pharmacology
ISSN:	1432-1041 0031-6970
Popis:	Purpose To analyze the clinical features and risk factors of tigecycline-associated hypofibrinogenaemia and study whether cefoperazone/sulbactam combined with tigecycline aggravates coagulopathy or hypofibrinogenaemia. Methods A retrospective case–control study of patients with severe infection who were treated with tigecycline was conducted. Patients were assigned to the hypofibrinogenaemia group (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac8dd393bd74a748ea3d41af109019ac https://doi.org/10.1007/s00228-020-02860-w Zobrazit plný text záznamu Full text from SpringerLink