The biosynthetic origin of diketopiperazines derived from D-proline

Autor:	Steven D. Bull, Richard M. Parkin, Francisco Sánchez-Sancho, Stephen G. Davies
Rok vydání:	1998
Předmět:	Sponge biology Chemistry Stereochemistry Proline biology.organism_classification Diketopiperazines Calyx
Zdroj:	Journal of the Chemical Society, Perkin Transactions 1. :2313-2320
ISSN:	1364-5463 0300-922X
DOI:	10.1039/a802702a
Popis:	Investigations reveal that the structures assigned to D-α-amino acid containing diketopiperazines (DKPs) 21-25 isolated from the sponge Calyx CF. podatypa have been reported incorrectly. Synthetic studies and comparison with literature data have enabled the structures of these DKPs to be correctly reassigned. Evidence is presented to suggest that naturally occurring D-Pro-L-Xxx-DKPs are artifacts resulting from non-enzymatic epimerisation of the corresponding L-Pro-L-Xxx-DKP natural products.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac8ac9ccc9f6d45afdf447e0a78b6e24 https://doi.org/10.1039/a802702a Zobrazit plný text záznamu