Effectiveness of porcine dermal collagen in giant hernia closure in patients with deleterious fascia constitution after orthotopic liver transplantation
| Autor: | H. Bacher, Florian Iberer, Peter Kornprat, Thomas Rappl, Mathias Wagner, Hans Jörg Mischinger, Doris Wagner, Georg Werkgartner, Daniela Kniepeiss, Herwig Cerwenka |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Swine Incisional hernia medicine.medical_treatment Biocompatible Materials macromolecular substances Abdominal wall Clinical endpoint Animals Humans Medicine Hernia Aged Transplantation business.industry hemic and immune systems Immunosuppression Fascia Middle Aged Surgical Mesh medicine.disease Hernia Ventral Fasciotomy Liver Transplantation Surgery surgical procedures operative medicine.anatomical_structure Female Collagen Implant business Wound healing Immunosuppressive Agents |
| Zdroj: | Transplant International. 28:156-161 |
| ISSN: | 0934-0874 |
| Popis: | Summary Incisional hernias (IHs) occur universally after orthotopic liver transplantation (OLT). This study aimed to investigate the effectiveness of porcine dermal collagen (PDC) as a closing aid in giant hernias after OLT in a prospective trial. If direct closure (DC) was not feasible due to the hernia size and abdominal wall constitution, a PDC mesh was implanted. All patients from the PDC and DC groups were followed prospectively for 24 months. IH recurrence rates served as the primary endpoint, and the development of infections and wound healing disorders served as the secondary endpoints. Recurrence rate was 21% (4/19) in DC patients and 12% (2/16) in PDC patients (P = 0.045). Implant site infections occurred in five of PDC and one of DC patients (P |
| Databáze: | OpenAIRE |
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