Impact of lymph node ratio on survival and recurrence outcomes in oral squamous cell carcinoma
| Autor: | M, Mamic, M, Lucijanic, M, Lorencin, P, Suton, I, Luksic |
|---|---|
| Rok vydání: | 2022 |
| Předmět: |
Squamous Cell Carcinoma of Head and Neck
Prognosis Otorhinolaryngology Head and Neck Neoplasms Lymphatic Metastasis Carcinoma Squamous Cell Humans Lymph Node Excision Mouth Neoplasms Surgery Lymph Nodes Neoplasm Recurrence Local lymph node ratio lymphatic metastasis mouth neoplasms neoplasm staging survival analysis Oral Surgery Lymph Node Ratio Neoplasm Staging Retrospective Studies |
| Zdroj: | International Journal of Oral and Maxillofacial Surgery. 51:1257-1263 |
| ISSN: | 0901-5027 |
| Popis: | Growing evidence supports the lymph node ratio (LNR) as a prognostic factor for survival in patients with oral squamous cell carcinoma (OSCC). However, there is a lack of data regarding its association with recurrence outcomes. Data on 163 patients with OSCC who underwent primary surgical treatment at a tertiary centre between January 2009 and December 2015 were collected retrospectively and analysed. Receiver operating characteristic curve analysis was performed to determine optimal cut-off values for the survival analyses. Survival endpoints were disease progression/relapse for disease-free time (DFT), freedom from loco-regional recurrence (FLR), and freedom from distant metastasis (FDM), and as death from any cause for overall survival (OS). Patients with a lower LNR were found to have significantly superior DFT (LNR < 14%, P < 0.001), FLR (LNR |
| Databáze: | OpenAIRE |
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